Celentyx Ltd | Immunology CRO
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Seahorse Metabolic Assays

Home > Services > Seahorse Metabolic Assays

Detailed metabolic profiling of immune cells such as B cells, dendritic cells, monocytes, macrophages, microglia, neutrophils, NK cells, T cells and others

Enables metabolic profiling of compounds including quantification of glycolytic rate and oxidative phosphorylation. Can be used for metabolic profiling of cells, understanding which nutrients are supporting cellular metabolism, and understanding the impact of compounds on mitochondria.
Further Services
Assays on Patient Cells
​Bespoke Services & Assay Development
​CYTOF
ELISA
​
​ELISpot
Flow cytometry
​Imaging: High Content
Luminex​​​
​Phosphoflow

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Mito Stress Test Cell persistence and fitness are tightly linked to mitochondrial function. This assay is the most comprehensive functional analysis of mitochondrial function. This test can be used with various types of cells and combined with the addition of a substrate or inhibitor to allow interrogation of three primary substrates that fuel the mitochondria: long chain fatty acids, glucose/pyruvate, and/or glutamine, facilitating investigation of how cells alter or shift oxidation of specific substrates to perform key cellular functions of activation, proliferation, and differentiation, as well as to respond to genetic or pharmaceutical interventions or survival in microenvironments.
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Glycolytic rate assay.  Probe glycolytic metabolism in real-time. Uses proton efflux rate and correction of mitochondrial acidification to provide a more robust and accurate way of assessing glycolysis within cells. Provides accurate measurements of basal glycolyic rates and compensatory glycolysis following mitochondrial inhibition.
​Assays may be suitable for testing the impact of modulators of immuno-metabolism.

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Celentyx Ltd
Birmingham Research Park
97 Vincent Drive
Birmingham
B15 2SQ
United Kingdom
Celentyx Innovation Lab
BioEscalator Innovation Building
Roosevelt Drive
Oxford
​OX3 7FZ
United Kingdom

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  • Home
  • Immunology Assays
    • B Cells
    • Haemolysis Testing
    • Human microglia
    • Macrophages/Monocytes
    • Neutrophils/Granulocytes
    • Phagocytosis Assays
    • Regulatory T cells
    • Spheroid Killing Assays
    • Suppression Assays
    • T Cells Activation Assays
    • T Cell Exhaustion Assays
    • TIL and dissociated tumour cell assays
    • Tumour Cell Killing
  • Therapeutic Area
    • Autoimmunity & Inflammation
    • COVID-19
    • Fibrosis
    • Immuno-oncology
    • Neuroinflammation
  • Services
    • Assays on Patient Cells
    • Bespoke Services & Assay Development
    • CyTOF
    • ELISA
    • ELISpot
    • ELLA
    • Flow Cytometry
    • Imaging: High-content
    • Luminex
    • Phosphoflow
    • Seahorse Metabolic Assays
  • About
    • People
    • Publications
    • News
    • Careers
  • Contact